[1]张剑*,边填轩,李辉,等.在微球透镜辅助下的成像研究[J].山东建筑大学学报,2021,36(02):53-60.[doi:10.12077/sdjz.2021.02.008]
 ZHANG Jian*,BIAN Tianxuan,LI Hui,et al.Super-resolution microscopy assisted by transparent dielectric microsphere imaging research with the aid of microsphere lens[J].Journal of Shandong jianzhu university,2021,36(02):53-60.[doi:10.12077/sdjz.2021.02.008]
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在微球透镜辅助下的成像研究()
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《山东建筑大学学报》[ISSN:1673-7644/CN:37-1449/TU]

卷:
36
期数:
2021年02期
页码:
53-60
栏目:
研究论文
出版日期:
2021-04-15

文章信息/Info

Title:
Super-resolution microscopy assisted by transparent dielectric microsphere imaging research with the aid of microsphere lens
文章编号:
1673-7644(2021)02-0053-08
作者:
张剑* 边填轩李辉张炆涛李萌萱
(山东建筑大学 理学院,山东 济南 250101)
Author(s):
ZHANG Jian* BIAN Tianxuan LI Hui ZHANG Wentao LI Mengxuan
( School of Science, Shandong Jianzhu University, Jinan 250101, China )
关键词:
介质微球分辨率放大率
Keywords:
dielectric microsphere resolution magnification
分类号:
O435.1
DOI:
10.12077/sdjz.2021.02.008
文献标志码:
A
摘要:
直径>200 μm的透明介质微球作为一种厚透镜可以提高显微镜成像的分辨率和放大率,是降低显微成本的有效方法。文章针对微球透镜的放大作用,在傍轴条件下,应用球面折射公式推导出透明介质微球焦点的位置,研究了当透明介质微球焦点到样品距离不同时的成实像和成虚像放大倍率,并且实验验证了透明介质微球增大分辨率和放大率的作用。结果表明:其放大率由微球焦点和样品的位置决定,分辨率则由焦点光斑的位置和直径决定,而两者都与微球的大小和折射率有关,其中透明硅胶微球辅助的显微图像的放大率是显微原图的10倍,而200 μm的钛酸钡微球可以实现125 nm的超分辨。
Abstract:
A transparent dielectric microsphere with diameter greater than 200 μm can be used as a thick lens to improve the resolution and magnification of microscope, which is an effective method to cut down the cost of microscope. In this paper, the focus position was inferred by the spherical refraction formula in the case of paraxial according to geometrical optics. Both real image and virtual image were studied at different distances between the focus and the sample theoretically and the increasing effect by the dielectric microsphere on the magnification and resolution was demonstrated by experiments. The results show that the magnification is determined by the position of the focus of the microsphere and the position of the sample and the resolution is determined by the position and diameter of the focus spot, both of which are related to the size and refractive index of the microsphere. The magnification of the image assisted by transparent dielectric microspheres is 10 times that of the original image. And the super-resolution of 125 nm can be achieved by 200 μm BaTiO3 microspheres.

参考文献/References:

[1]姚启钧. 光学教程[M].第5版.北京:高等教育出版社,1999. [2]CHEN Z G, ALLEN T. Photonic nanojet enhancement of backscattering of light by nanoparticles: A potential novel visible-light ultramicroscopy technique [J]. Optics Express, 2004(12):1214-1220. [3]刘帅,叶燃,曹玲玲.一种可移动超分辨成像系统的制备及其性质研究[J].应用光学,2014,35(3):427-431. [4]庞辉,杜春雷,邱琪,等.介质微球超分辨成像薄膜[J].光子学报,2015,44(4):0426004. [5]WANG H T, WU X, SHEN D Y. Trapping and manipulating nanoparticles in photonic nanojets [J]. Optics Letters, 2016(41):1652-1655. [6]WANG H T, ZHANG J N, WU X, et al. On-resonance photonic nanojets for nanoparticle trapping [J]. Optics Express, 2019(27):10472-10481. [7]徐伟,袁群,高志山,等.微球透镜超分辨显微成像与检测技术综述[J].应用光学,2019,40(6):1139-1151. [8]刘畅,金璐頔,叶安培.微球透镜超分辨成像研究进展与发展前景[J].激光与光电子学进展,2016,53:070003. [9]曹玲玲,姚岭,任杰,等.微球尺寸对其超分辨成像性质的影响[J].南京师大学报(自然科学版),2014,37(3):48-53. [10]ZHU J L, GODDARD L L. Spatial control of photonic nanojets [J]. Optics Express, 2016(24):30444-30464. [11]YANG J N, TWARDOWSKI P, GERARD P, et al. Ultra-narrow photonic nanojets through a glass cuboid embedded in a dielectric cylinder [J]. Optics Express, 2018(26):3723-3731. [12]LIN C B, HUANG Z H, LIU C Y. Formation of high-quality photonic nanojets by decorating spider silk[J]. Optics Letters, 2016(44):667-670. [13]ZHEN Z S, HUANG Y, FENG Y H, et al. An ultranarrow photonic nanojet formed by an engineered two-layer microcylinder of high refractive-index materials [J]. Optics Express, 2019(27):9178-9188. [14]GU G Q, SHAO L Y, SONG J, et al. Photonic hooks from Janus microcylinders [J]. Optics Express, 2019(27):37771-37780. [15]LIU C Y, YEH M J. Experimental verification of twin photonic nanojets from a dielectric microcylinder [J]. Optics Letters, 2019(44):3262-3265. [16]YANG S L, WANG F G, YE Y H, et al. Influence of the photonic nanojet of microspheres on microsphere imaging [J]. Optics Express, 2017, 25:27551-27558. [17]郭明磊.基于光子纳米喷流效应的微透镜超分辨成像[D]. 南京:南京师范大学, 2017. [18]周锐,吴梦雪,沈飞,等.基于近场光学的微球超分辨显微效应[J].物理学报,2017,66(14):140702. [19]陈涛,孟凯,杨湛,等.面向超分辨光学成像的浸没微球透镜控制[J].光学精密工程,2018,26(5):1106-1112.

备注/Memo

备注/Memo:
收稿日期:2020-03-02 基金项目:山东建筑大学博士基金项目(XNBS1715);山东建筑大学国家级创新创业项目(201910430029)作者简介:张剑(1978-),男,副教授,博士,主要从事光学成像等方面的研究。E-mail:gull_sea@sdjzu.edu.cn[*通讯作者]
更新日期/Last Update: 2021-04-15